
姓名:吳靜
職務:教授
院系:流行病與衛生統計學系
地址:湖北省武漢市航空路13号 430030
電話: 86-27-83657659
郵箱:wujingtj@hust.edu.cn
教育工作經曆:
1997.9-2002.6 8858ccl8利网址同濟醫學院兒少衛生與婦幼保健專業學士
2002.9-2007.6 8858ccl8利网址同濟醫學院兒少衛生與婦幼保健專業博士
2007.7-2012.10 8858ccl8利网址同濟醫學院8858ccl8利官网 講師
2012.11-2020.10 8858ccl8利网址同濟醫學院8858ccl8利官网 副教授
2020.11-至今 8858ccl8利网址同濟醫學院8858ccl8利官网 教授
吳靜,女,教授,博士生導師。2002年6月畢業于8858ccl8利网址同濟醫學院兒少衛生與婦幼保健專業,碩博連讀,2007年6月在8858ccl8利网址同濟醫學院獲兒少衛生與婦幼保健專業博士學位。同年7月留校,在8858ccl8利官网流行病與衛生統計學系擔任教師至今。主要研究方向:兒童神經精神發育疾病(注意缺陷多動障礙等)的相關遺傳标志物及其功能;生物統計學方法在健康保險中的應用。作為負責人已主持課題10餘項;發表論文約40篇,其中SCI收錄30餘篇;作為副主編出版教材2部和論著1部。兼任湖北省預防醫學會流行病學分會常委、武漢市預防醫學會衛生統計專業委員會委員、中國醫療保險研究會會員。獲8858ccl8利网址2017-2018學年度教學質量優秀獎二等獎;8858ccl8利网址醫科2017年優秀教學論文獎;2011年獲8858ccl8利网址教學質量優秀獎二等獎和8858ccl8利网址青年教師教學競賽二等獎;2007年度、2009年度和2014年度中國醫療保險研究會優秀研究論文二等獎。
主要負責的科研項目:
1. 基于谷氨酸突觸發育通路的注意缺陷多動障礙易感基因篩選及其神經影像學效應研究,國家自然科學基金項目(81773456),2018.1-2021.12,60.0萬,負責人
2. 鉀離子信号網絡基因遺傳變異與注意缺陷多動障礙易感性研究,國家自然科學基金項目(81101016),2012.1-2014.12,21.0萬,負責人
3. 基于谷氨酸突觸發育通路的注意缺陷多動障礙易感基因篩選與功能研究,8858ccl8利网址自主創新研究基金項目(2016YXM218),2016.4-2018.12,5.0萬,負責人
4. 醫學隊列大數據分析中數據粒度尺度對挖掘期望的影響研究,8858ccl8利网址自主創新研究基金項目(2014TS049),2014.4-2015.12,5.0萬,負責人
5. 基于生物節律調控網絡的結直腸癌易感基因識别和确認,8858ccl8利网址自主創新研究基金項目(2011QN200),2011.6-2012.12,5.0萬,負責人
6. 基于病種分析的醫改對縣級醫院醫療行為影響評價,強生上海醫療器材有限公司委托項目,2011.8-2012.7,100.0萬,負責人
7. 城鎮居民基本醫療保險門診統籌支付政策研究,人力資源和社會保障部2011年重大政策研究項目,2011.9-2012.2,10.0萬,負責人
8. 深圳人口老齡化對醫療保險基金壓力的預警研究,深圳市社會保險基金管理局委托項目,2011.6-2011.12,15.0萬,負責人
9. 醫療保險“一卡通”技術标準體系研究,中國醫療保險研究會2009年專項,2009.7-2010.6,40.0萬,負責人
10. 吻合器機械縫合技術在中國二級市場應用的衛生經濟學研究,強生上海醫療器材有限公司委托項目,2009.10-2010.6,46.5萬,負責人
11. 性健康幹預項目評價體系研究,8858ccl8利网址醫科科學研究基金項目,2008.1-2009.12,負責人
12. 青少年性健康行為的早期幹預研究,湖北省教育廳“十一五”規劃重點課題,2007.9-2008.8,負責人
代表性論著:
1. Zhang Q, Chen XZ, Li SY, Yao T, Wu J*. Association between the group III metabotropic glutamate receptor gene polymorphisms and attention-deficit/hyperactivity disorder and functional exploration of risk loci. J Psychiatr Res. 2021 Jan;132:65-71.
2. Zhang Q, Huang X, Chen X, Li SY, Yao T, Wu J*. Association of gene variations in ionotropic glutamate receptor and attention-deficit/hyperactivity disorder in the Chinese population: a two-stage case-control study. J Atten Disord. 2021 Aug;25(10):1362-1373.
3. Zhang Q, Chen XZ, Huang X, Wang M, Wu J*. The association between prenatal exposure to phthalates and cognition and neurobehavior of children-evidence from birth cohorts. Neurotoxicology. 2019 Jul;73:199-212.
4. Huang X, Zhang Q, Chen X, Gu X, Wang M, Wu J*. A functional variant in SLC1A3 influences ADHD risk by disrupting a hsa-miR-3171 binding site: A two-stage association study. Genes Brain Behav. 2019 Jun;18(5):e12574.
5. Chen X, Wang M, Zhang Q, Hou Y, Huang X, Li S, Wu J*. Stress response genes associated with attention deficit hyperactivity disorder: A case-control study in Chinese children. Behav Brain Res. 2019 May 2; 363: 126-134.
6. Wang M, Gu X, Huang X, Zhang Q, Chen X, Wu J*. STX1A gene variations contribute to the susceptibility of children attention-deficit/hyperactivity disorder: a case-control association study. Eur Arch Psychiatry Clin Neurosci. 2019 Sep;269(6):689-699.
7. Huang X, Wang M, Zhang Q, Chen X, Wu J*. The role of glutamate receptors in attention-deficit/hyperactivity disorder: From physiology to disease. Am J Med Genet B Neuropsychiatr Genet. 2019 Jun;180(4):272-286.
8. Huang X, Zhang Q, Gu X, Hou Y, Wang M, Chen X, Wu J*. LPHN3 gene variations and susceptibility to ADHD in Chinese Han population: a two-stage case-control association study and gene-environment interactions. Eur Child Adolesc Psychiatry. 2019 Jun;28(6):861-873.
9. Gu X, Yuan FF, Huang X, Hou Y, Wang M, Lin J, Wu J*. Association of PIK3CG gene polymorphisms with attention-deficit/hyperactivity disorder: A case-control study. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Feb 2; 81: 169-177.
10. Hou YW, Xiong P, Gu X, Huang X, Wang M, Wu J*. Association of Serotonin Receptors with Attention Deficit Hyperactivity Disorder: A Systematic Review and Meta-analysis. Curr Med Sci. 2018 Jun; 38(3): 538-551.
11. Yuan FF, Gu X, Huang X, Hou YW, Zhong Y, Lin J, Wu J*. Attention-deficit/hyperactivity disorder associated with KChIP1 rs1541665 in Kv channels accessory proteins. PLoS One. 2017 Nov 27; 12(11): e0188678.
12. Yuan FF, Gu X, Huang X, Zhong Y, Wu J*. SLC6A1 gene involvement in susceptibility to attention-deficit/hyperactivity disorder: A case-control study and gene-environment interaction. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Jul 3; 77: 202-208.
13. Liu YS, Dai X, Wu W, Yuan FF, Gu X, Chen JG, Zhu LQ*, Wu J*. The association of SNAP25 gene polymorphisms in attention deficit hyperactivity disorder: a systematic review and meta-analysis. Mol Neurobiol, 2016, 54(3): 1-12.
14. Liu DY, Shen XM, Yuan FF, Guo OY, Zhong Y, Chen JG, Zhu LQ*, Wu J*. The physiology of BDNF and its relationship with ADHD. Mol Neurobiol, 2015, 52(3):1467-1476.
15. Sun H, Yuan F, Shen X, Xiong G, Wu J*. Role of COMT in ADHD: A systematic meta-analysis. Mol Neurobiol, 2014, 49(1): 251-261.
16. Xu Q, Yuan F, Shen X, Wen H, Li W, Cheng B, Wu J*. Polymorphisms of C242T and A640G in CYBA gene and the risk of coronary artery disease: a meta-analysis. PLoS One, 2014 Jan; 9(1): e84251.
17. Zheng C*, Zhang J, Wu J*, Zhang MM. The effect of transcutaneous electrical acupoint stimulation on pregnancy rates in women undergoing in vitro fertilization: a study protocol for a randomized controlled trial. Trials, 2014 May 9; 15:162.
18. Liu L, Wu J, Zhong R, Wu C, Zou L, Yang B, Chen W, Zhu B, Duan S, Yu D, Tan W, Nie S, Lin D, Miao X*. Multi-loci analysis reveals the importance of genetic variations in sensitivity of platinum-based chemotherapy in non-small-cell lung cancer. Mol Carcinog, 2013 Dec; 52(12): 923-931.
19. Wu J, Xiao H, Sun H, Zou L, Zhu LQ*. Role of Dopamine Receptors in ADHD: A systematic meta-analysis. Mol Neurobiol, 2012, 45(3): 605-620.
20. Lou J, Xu S, Zou L, Zhong R, Zhang T, Sun Y, Lu X, Liu L, Li C, Wang L, Xiong G, Wang W, Gong F, Wu J*. A functional polymorphism, rs28493229, in ITPKC and risk of Kawasaki disease: an integrated meta-analysis. Mol Biol Rep, 2012, 39(12): 11137-11144.
21. Liu L, Wu J, Wu C, Wang Y, Zhong R, Zhang X, Tan W, Nie S, Miao X*, Lin D*. A functional polymorphism (-1607 1G→2G) in the matrix metalloproteinase-1 promoter is associated with development and progression of lung cancer. Cancer, 2011, 117(22): 5172-5181. (Co-first author)
22. Huang S, Hu X, Chen H, Xie D, Gan X, Wu Y, Nie S*, Wu J*. The positive effect of an intervention program on the hypertension knowledge and lifestyles of rural residents over the age of 35 years in an area of China. Hypertens Res, 2011, 34(4): 503-508.
23. Li J, Sun C, Yuan Y, Liu L, Xiong G, Wu J*. Bone morphogenetic protein-4 polymorphism and colorectal cancer risk: a meta analysis. Mol Biol Rep, 2012, 39(5): 5239-5251.
24. Chen G, Quan S, Hu Q, Wang L, Xia X*, Wu J*. Lack of association between MDR1 C3435T polymorphism and chemotherapy response in advanced breast cancer patients: evidence from current studies. Mol Biol Rep, 2012, 39(5): 5161-5168.
25. Wang W, Fan Y, Xiong G, Wu J*. Nitrate in drinking water and bladder cancer: A meta-analysis. J Huazhong Univ Sci Technolog Med Sci, 2012, 32(6): 912-918.
26. 劉起,張琦,黃向,田立黎,程自秀,蔡蓮蓮,吳靜*.基于氣質的學齡前兒童行為問題結構方程模型的研究.中國婦幼保健,2013,28(3):436-438.
27. 鮑振陽,譚宇,熊光練,吳靜*.深圳市醫療費用預測分析及醫療保險基金管理對策研究.中國社會醫學雜志,2013,30(5):350-352.
28. 吳靜*,嚴薇榮,魏晟,聶紹發,劉雲升,戴璇,黃馨.基于E-learning平台的流行病學案例庫的開發與實踐.中國高等醫學教育,2017,(3):24-25.
29. 副主編,《臨床流行病學》,北京:人民衛生出版社,2021.5(ISBN 978-7-117-31232-5)
30. 編委,《現場流行病學》,北京:人民衛生出版社,2017.4(ISBN 9787117238182)
31. 副主編,《醫療保險國際比較》,北京:科學出版社,2015.7,全國高等學校醫療保險專業第一輪規劃教材(ISBN 9787030452573)
32. 副主編,《兒童身心發展與情、智商潛力開發》,武漢出版社,2006.12(ISBN 7-5430-3573-1)