個人簡介

2004年和2007年畢業于8858ccl8利网址同濟醫學院8858ccl8利官网勞動衛生與環境衛生學系，分别獲碩士和博士學位。2009年－2010年在美國哈佛大學8858ccl8利官网從事博士後研究工作。2010受聘于8858ccl8利网址同濟醫學院8858ccl8利官网。

  主要從事慢性代謝性疾病環境流行病學和分子流行病學方面的研究工作，近年來先後主持和參與國家基金委、科技部基礎專項和科技部重點研發計劃等多項科研項目，在環境流行病學和慢性病分子流行病學研究方面取得了一系列研究成果，共在國際權威期刊發表SCI論文100多篇。其中第一作者或者通訊作者文章超過50篇，包括Circulation、GUT、Hepatology、Diabetologia、Arterioscler Thromb Vasc Biol、Human Molecular Genetics、Indoor Air、Environmental Pollution和J Nutrition等雜志。擔任《環境與職業醫學》和PLoS ONE等雜志編委。

研究方向

· 通過前瞻性的隊列研究深入探讨代謝綜合征、2型糖尿病、心腦血管疾病等慢性疾病及其并發症發生發展的主要環境因素和遺傳因素，以及遺傳-環境（重金屬、環境内分泌幹擾物、生活方式等）和遺傳-表型間的相互作用，建立早期預測和高危個體篩選模型；

· 利用系統流行病學和多組學的方法深入探讨環境相關疾病的發病機制，尋找新的生物标志物，為個性化醫療和轉化醫學提供科學支持。

代表性論著

1. Wang F, Wang J, Li Y, Yuan J, Yao P, Wei S, Guo H, Zhang X, Yang H, Wu T, He M. Gallstone Disease and Type 2 Diabetes Risk: A Mendelian Randomization Study. Hepatology. 2018 Dec 4. doi: 10.1002/hep.30403

2. Wang F, Wang J, Li Y, Han X, Hu H, Yu C, Yuan J, Yao P, Miao X, Wei S, Wang Y, Chen W, Liang Y, Guo H, Zhang X, Yang H, Wu T, He M. Associations between daily cooking duration and the prevalence of diabetes and prediabetes in a middle-aged and elderly Chinese population: A cross-sectional study. Indoor Air. 2018 Mar; 28(2):238-246. doi: 10.1111/ina.12434.

3. Wang J, Yu Y, Li X, Li D, Xu C, Yuan J, Wei S, Li X, Yang K, Zheng D, Tang Y, Yang H, Wu T, He M. Serum uric acid levels and decreased estimated glomerular filtration rate in patients with type 2 diabetes: A cohort study and meta-analysis. Diabetes Metab Res Rev. 2018 Oct; 34(7):e3046. doi: 10.1002/dmrr.3046.

4. Yu C, Wang J, Wang F, Han X, Hu H, Yuan J, Miao X, Yao P, Wei S, Wang Y, Liang Y, Zhang X, Guo H, Pan A, Zheng D, Tang Y, Yang H, Wu T, He M. Victims of Chinese famine in early life have increased risk of metabolic syndrome in adulthood. Nutrition. 2018 Sep; 53:20-25. doi: 10.1016/j.nut.2017.12.013.

5. Han X, Wang J, Li Y, Hu H, Li X, Yuan J, Yao P, Miao X, Wei S, Wang Y, Liang Y, Zhang X, Guo H, Pan A, Yang H, Wu T, He M. Development of a new scoring system to predict 5-year incident diabetes risk in middle-aged and older Chinese. Acta Diabetol. 2018; 55(1):13-19. doi: 10.1007/s00592-017-1047-1.

6. Han X, Wang Z, Wang J, Li Y, Hu H, Hu Y, Zhao X, Zhan Y, Yuan J, Wei S, Liang Y, Zhang X, Guo H, Yang H, Wu T, Kong W, He M. Metabolic syndrome is associated with hearing loss among a middle-aged and older Chinese population: a cross-sectional study.Ann Med. 2018 Nov; 50(7):587-595. doi: 10.1080/07853890.2018.1469786.

7. Yu C, Wang J, Li Y, Han X, Hu H, Wang F, Yuan J, Yao P, Miao X, Wei S, Wang Y, Chen W, Liang Y, Zhang X, Guo H, Yang H, Wu T, He M. Exposure to the Chinese famine in early life and hypertension prevalence risk in adults. J Hypertens. 2017 Jan; 35(1):63-68.

8. Wang J, Wu X, Li Y, Han X, Hu H, Wang F, Yu C, Li X, Yang K, Yuan J, Yao P, Miao X, Wei S, Wang Y, Chen W, Liang Y, Guo H, Yang H, Wu T, Zhang X, He M. Serum bilirubin concentrations and incident coronary heart disease risk among patients with type 2 diabetes: the Dongfeng-Tongji cohort. Acta Diabetol. 2017 Mar; 54(3):257-264. doi: 10.1007/s00592-016-0946-x.

9. Liu B, Feng W, Wang J, Li Y, Han X, Hu H, Guo H, Zhang X, He M.

10. Association of urinary metals levels with type 2 diabetes risk in coke oven workers. Environ Pollut. 2016 Mar; 210:1-8. doi: 10.1016/j.envpol.2015.11.046.

11. Wang J, Li Y, Han X, Liu B, Hu H, Wang F, Li X, Yang K, Yuan J, Yao P, Miao X, Wei S, Wang Y, Liang Y, Zhang X, Guo H, Yang H, Hu FB, Wu T, He M. Exposure to the Chinese Famine in Childhood Increases Type 2 Diabetes Risk in Adults. J Nutr. 2016 Nov; 146(11):2289-2295.

12. He M, Xu M, Zhang B, et al. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Hum Mol Genet. 2015 Mar 15; 24(6):1791-800. doi: 10.1093/hmg/ddu583.

13. He M, Wu C, Xu J, Guo H, Yang H, Zhang X, Sun J, Yu D, Zhou L, Peng T, He Y, Gao Y, Yuan J, Deng Q, Dai X, Tan A, Feng Y, Zhang H, Min X, Yang X, Zhu J, Zhai K, Chang J, Qin X, Tan W, Hu Y, Lang M, Tao S, Li Y, Li Y, Feng J, Li D, Kim ST, Zhang S, Zhang H, Zheng SL, Gui L, Wang Y, Wei S, Wang F, Fang W, Liang Y, Zhai Y, Chen W, Miao X, Zhou G, Hu FB, Lin D, Mo Z, Wu T. A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk. Gut. 2014 Jan; 63(1):143-51. doi: 10.1136/gutjnl-2012-303434.

14. Gui L, Wu F, Han X, Dai X, Qiu G, Li J, Wang J, Zhang X, Wu T, He M. A multilocus genetic risk score predicts coronary heart disease risk in a Chinese Han population. Atherosclerosis. 2014 Dec; 237(2):480-5.

15. Dai X, Yuan J, Yao P, Yang B, Gui L, Zhang X, Guo H, Wang Y, Chen W, Wei S, Miao X, Li X, Min X, Yang H, Fang W, Liang Y, Hu FB, Wu T, He M. Association between serum uric acid and the metabolic syndrome among a middle- and old-age Chinese population. Eur J Epidemiol. 2013 Aug; 28(8):669-76. doi: 10.1007/s10654-013-9829-4.

16. Shi Y, Zhou L, Huang LH, Lian YT, Zhang XM, Guo H, Wu TC, Cheng LX, He M. Plasma ferritin levels, genetic variations in HFE gene, and coronary heart disease in Chinese: a case-control study. Atherosclerosis. 2011; 218(2):386-90.

17. He M, Workalemahu T, Cornelis MC, Hu FB, Qi L. Genetic variants near IRS1 gene, physical activity, and type 2 diabetes in US men and women. Diabetologia. 2011; 54(6):1579-82.

18. He M, van Dam RM, Rimm E, Hu FB, Qi L. Whole grain, cereal fiber, bran, and germ intake and the risks of all-cause and CVD-specific mortality among women with type 2 diabetes. Circulation. 2010; 121(20):2162-2168.

19. He M, Cornelis MC, Franks PW, Zhang C, Hu FB, Qi L. Obesity genotype score and cardiovascular risk in women with type 2 diabetes mellitus. Arterioscler Thromb Vasc Biol. 2010; 30(2):327-332.

20. He M, Cornelis MC, Kraft P, van Dam RM, Sun Q, Laurie CC, Mirel DB, Chasman DI, Ridker PM, Hunter DJ, Hu FB, Qi L. Genome-Wide Association Study Identifies Variants at the IL18-BCO2 Locus Associated With Interleukin-18 Levels.Arterioscler Thromb Vasc Biol. 2010; 30(4):885-890.

招生信息

  接收本科生2-3人/年進行科研培訓，招收碩士生和博士生4-5人/年，常年招收博士後。有意者請通過郵件聯系。